18 Coronavirus Autopsies (This is what they found in the Brain) | COVID-19

If you’ve seen my previous videos on autopsies that were done on COVID-19 patients, it’s pretty clear by now that when patients do die of this coronavirus, it’s because of the lungs. Either because of all the inflammation in the lungs, with pneumonia and cytokine storm and ARDS, sometimes with multiorgan failure….or because of the major blood clot that develops in the lungs. Sometimes though, blood clots show up in other parts of the body as well. For example, in some cases, clots can travel to the brain, and lodge in the blood vessels there, causing decreased blood flow to certain regions of the brain, and this is known as a stroke. But this virus, in a different manner, can cause neurologic symptoms in some people, such as headache, confusion, and anosmia, meaning loss of taste and smell. But we don’t really know why this coronavirus sometimes causes these symptoms. Is it because the coronavirus travels in the bloodstream to the brain? Maybe. After all, there are ACE2 receptors that are located in the brain. Is it because the virus gets in our nose, and used the olfactory nerves that are there to gain entry into our brain? Or are these symptoms more related to the effects of the cytokine storm, which is actually pretty common with infections in general, whether that be from pneumonia or something else? In a recent study in NEJM, they looked at brain findings from autopsies done on 18 patients who died from COVID-19, in a single teaching hospital. All 18 of these patients had nasopharyngeal swab samples that were positive for SARS-CoV-2 on RT-PCR. Eleven COVID 19 patients required mechanical ventilation, meaning a breathing tube. Interestingly, it was noted that all of the ventilated patients had a confusional state or decreased arousal from sedation for ventilation. The way that I interpret this is that when they paused the sedation, meaning they temporarily stopped the sedation to assess their mental status, the patient was able to follow commands during that time. This, in general, is not uncommon, but this does seem to occur more often with COVID 19 patients, and this is something that I’ve been finding with my COVID 19 patients in the ICU. On average, these COVID-19 patients died about 10 days after being admitted to the hospital. When they did the autopsies, they looked at the brain as a whole, and they also sampled 10 different areas of the brain, and then looked at those samples underneath the microscope. Microscopic examination showed acute hypoxic injury in some regions of the brain. Acute hypoxic injury means tissue was damaged as a result of not getting enough oxygen. There was an acute hypoxic injury in the cerebrum, which is the part of the brain that allows us to think, and be conscious. There was also an acute hypoxic injury in the cerebellum in all the patients. There were no blood clots in the brain, or vasculitis, meaning inflammation of blood vessels. So another thing we want to know, is, is the virus actually invading the cells of the brain? In this study, they actually tested the brain tissue for the virus with RT-PCR. Dr. Mike Hansen, MD Internal Medicine | Pulmonary Disease | Critical Care Medicine Website: https://doctormikehansen.com/ Instagram Account: http://instagram.com/doctor.hansen/

Outbreak Onboard: How fear and disease spread on the Ruby Princess | Four Corners

The Ruby Princess cruise ship is the single largest source of COVID-19 infections in Australia. Owned by the world’s largest cruise company, Carnival Corporation, the Ruby Princess was one of a fleet of cruise ships operating as the pandemic gathered speed. The company was well aware of the risks. Only five weeks earlier its sister ship, the Diamond Princess, created world headlines when its passengers were trapped on board as the virus spread. On March 19, thousands of its passengers disembarked from the Ruby Princess in Sydney before dispersing around the country and overseas. Far from protecting people, the release of its passengers triggered a public health emergency. Four Corners investigates how the Ruby Princess became an incubator for infection, leaving its passengers and staff dangerously exposed. We also examine the actions of Australian authorities who allowed the ship to dock and the passengers to disembark, taking the virus with them. Read more: https://ab.co/2Xql3Q6 _________ 

Wise Words

“. . . the “new normal” will be like nothing we have ever experienced. . . “

hughcurtler

I have no idea who wrote the following piece, but it strikes me as worthy of wider dissemination than it has had so far. My son sent it to me the other day and said, simply, “it was written by a co-worker.” It strikes me as particularly important given the fact that we are all feeling fed-up with the coronavirus and all that it entails. We simply cannot wait until things go “back to normal” — refusing to admit to ourselves that there may be no return to normal and that the “new normal” will be like nothing we have ever experienced.

In any event, we wallow in self-pity since few of us has ever had to deny ourselves much of what we want. This is, after all, the “Age of Entitlement” not only in the schools but in the homes as well. We buy on plastic and run up…

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